TechSurge: Deep Tech Podcast
Exploring topics at the intersection of emerging technology, geopolitics, and business.
Hosted by Celesta Capital.
The TechSurge: Deep Tech VC Podcast shares the latest insights directly from legendary Silicon Valley leaders, daring new founders, and visionary technologists.
Join us as we examine the factors shaping the next major technology cycle shift of AI, examine emerging global tech hubs, and analyze where investment dollars are flowing next.
Each discussion delves into the intersection of technology advancement, market dynamics, and the founder journey, offering insights into the vast opportunities and complex challenges ahead.
For entrepreneurs, investors, or anyone interested in where we're headed next, this is your guide to understanding the technologies and companies poised to transform the future.
Pixels to Intelligence: The Next Era of Imaging
Digital imaging is so ubiquitous today that it’s easy to forget how improbable it once was. In this episode of TechSurge, guest host Nic Brathwaite sits down with Dr. Eric Fossum, inventor of the CMOS active pixel image sensor, to unpack the breakthrough that made it possible to embed cameras into billions of devices and the deeper lessons behind it.
Eric explains how his work began not with consumer electronics, but with a NASA constraint: how to shrink a refrigerator-sized space camera into something small enough for spacecraft. The solution required a fundamental shift in architecture. By moving from CCD-based imaging to CMOS, where sensing and processing could happen on a single chip, he enabled a level of miniaturization and scalability that transformed cameras from standalone systems into embedded infrastructure.
But the conversation goes far beyond the invention itself. Nic and Eric explore what it takes to commercialize deep technology, from the early days of Photobit to its acquisition by Micron, and the critical role ecosystems play in turning breakthroughs into global platforms. They discuss why intellectual property is less about protection and more about leverage, and why even the most important inventions require manufacturing scale, capital, and partnerships to succeed.
The episode also looks forward. As AI systems increasingly rely on visual and physical data, sensors are shifting from tools designed for human perception to components optimized for machine intelligence. Eric highlights the challenges of pushing intelligence to the edge, the limitations of current architectures, and the growing importance of sensing technologies beyond traditional imaging—including molecular detection and new materials that go beyond silicon.
While much of today’s investment is concentrated in models and compute, this conversation makes the case that the next wave of innovation may come from deeper layers of the stack, where machines interact directly with the physical world. The future of AI may depend not just on how systems think, but on how they see, detect, and understand their environment.
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Micron CEO Sanjay Mehrotra discusses his journey in the semiconductor industry and the growing strategic importance of the memory industry in the age of AI. He highlights innovation in high bandwidth memory (HBM), which enables faster data access and lower power consumption. Sanjay also discusses Micron’s plans to build new U.S. semiconductor factories and the role of the CHIPS Act in bringing semiconductor manufacturing back to the U.S. He shares his insights on the resurgence of hardware innovation and what it takes to drive technological leadership in a rapidly evolving industry.
Former CEO of PepsiCo and New York Times bestselling author Indra Nooyi joins host Michael Marks for a wide-ranging conversation to share her insights on the growth of big tech companies, the impact of AI, CEO-board relationships, and much more.
Indra currently serves on the boards of Amazon, Phillips, Memorial Sloan Kettering Cancer Center, the National Gallery of Art, and is a Dean’s Advisory Council Member at MIT School of Engineering. Her New York Times bestselling memoir My Life In Full offers insight and a call-to-action from one of the world’s most-admired business leaders on how our society can blend work and family — and advance women — in the 21st century. She is widely considered to be one of the world’s top CEOs for her leadership at global giant PepsiCo over 12 years.
Driven both by surging demand and rapid technology advancements, an emerging area of health innovation called “bioconvergence” is driving improvements in human health and sustained interest from investors. This episode will explore these new applications merging engineered technologies with scientific disciplines, including in diagnostics, therapeutics, and elsewhere.
Nobel Laureate Dr. Jim Rothman, Dr. Melanie Mathieu of Prellis Biologics, and Daniel Dornbusch of Excision join host Michael Marks for an in-depth discussion covering advancements in CRISPR technology, the role of AI in drug discovery, the future of personalized medicine, and much more.
Legendary technology founder and venture investor Vinod Khosla joins host Michael Marks for a wide-ranging discussion on the future of AI, major tech cycles, the importance of being honest with founders, and much more. Vinod shares his predictions for the next 25 years of technology advancement and how we should be assessing the risks and benefits as the adoption of artificial intelligence continues to accelerate.
Celesta Capital is a global deep tech venture firm enabling visionary founders at the forefront of scientific and engineering breakthroughs.
Celesta's team has spent decades founding, leading, and scaling global technology businesses, collectively founding more than 40 companies. We understand how to partner with founders to help turn prototypes into powerhouses.
From semiconductors and systems to breakthrough biology, we seek out the physics‑defying, code‑rewriting breakthroughs that will power the next decade of technology advancement.
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