TechSurge: Deep Tech Podcast
Exploring topics at the intersection of emerging technology, geopolitics, and business.
Hosted by Celesta Capital.
The TechSurge: Deep Tech VC Podcast shares the latest insights directly from legendary Silicon Valley leaders, daring new founders, and visionary technologists.
Join us as we examine the factors shaping the next major technology cycle shift of AI, examine emerging global tech hubs, and analyze where investment dollars are flowing next.
Each discussion delves into the intersection of technology advancement, market dynamics, and the founder journey, offering insights into the vast opportunities and complex challenges ahead.
For entrepreneurs, investors, or anyone interested in where we're headed next, this is your guide to understanding the technologies and companies poised to transform the future.
The US Crypto Awakening
For years, crypto policy in the United States was defined less by clear rules than by the threat of enforcement. Startups and institutions building in the space operated in a gray zone: no clear guidance, no path to compliance, and always the possibility of a regulatory hammer coming down. In 2025, that began to change.
In this episode of TechSurge, host Sriram Viswanathan speaks with Commissioner Hester Peirce of the U.S. Securities and Exchange Commission — one of Washington's most closely watched voices on digital asset policy. Known informally as "Crypto Mom" for her consistent advocacy that markets work best with clear rules and room to innovate, Commissioner Peirce was designated in 2025 to lead the SEC's first Crypto Task Force, signaling a more structured, collaborative approach to digital asset regulation.
Commissioner Peirce brings a rare perspective: a regulator who believes that ambiguity does not protect investors — it protects incumbents and rewards bad actors. In this conversation, she explains what has actually changed in 2025, what it means for companies building in crypto, and what it will take to make this regulatory progress durable beyond any single administration.
Sriram and Commissioner Peirce work through the full landscape: why "crypto" is not one thing but several, how the SEC thinks about Bitcoin as a commodity, what tokenization of traditional securities actually requires, and where real policy gaps remain. They also examine the role of stablecoins and CBDCs, the tension between investor protection and permissionless innovation, and how vertical integration in crypto markets raises the same questions the financial system has always faced — just with new architecture underneath.
Ultimately, Commissioner Peirce argues that the best regulatory framework is one that lets markets identify where technology is useful, enforces rules fairly and consistently, and makes enough room for people to build real things that solve real problems. Once those products exist and are woven into daily economic life, she argues, they become durable — regardless of who is in office.
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Fred Thiel, Chairman and CEO of Marathon Digital, dives us into the world of blockchain and cryptocurrency mining. Fred discusses the technological advancements in Bitcoin mining, including significant improvements in energy efficiency, and provides insights into the future of Bitcoin, predicting substantial growth in its value and its linkages with AI inference data centers. He also explains the relationship between Bitcoin and global economic factors, the potential for regulatory changes, and the evolving role of cryptocurrencies in both developed and developing markets, highlighting Bitcoin’s growing role as a store of value and a driver of financial sovereignty in the digital age.
Micron CEO Sanjay Mehrotra discusses his journey in the semiconductor industry and the growing strategic importance of the memory industry in the age of AI. He highlights innovation in high bandwidth memory (HBM), which enables faster data access and lower power consumption. Sanjay also discusses Micron’s plans to build new U.S. semiconductor factories and the role of the CHIPS Act in bringing semiconductor manufacturing back to the U.S. He shares his insights on the resurgence of hardware innovation and what it takes to drive technological leadership in a rapidly evolving industry.
Former CEO of PepsiCo and New York Times bestselling author Indra Nooyi joins host Michael Marks for a wide-ranging conversation to share her insights on the growth of big tech companies, the impact of AI, CEO-board relationships, and much more.
Indra currently serves on the boards of Amazon, Phillips, Memorial Sloan Kettering Cancer Center, the National Gallery of Art, and is a Dean’s Advisory Council Member at MIT School of Engineering. Her New York Times bestselling memoir My Life In Full offers insight and a call-to-action from one of the world’s most-admired business leaders on how our society can blend work and family — and advance women — in the 21st century. She is widely considered to be one of the world’s top CEOs for her leadership at global giant PepsiCo over 12 years.
Driven both by surging demand and rapid technology advancements, an emerging area of health innovation called “bioconvergence” is driving improvements in human health and sustained interest from investors. This episode will explore these new applications merging engineered technologies with scientific disciplines, including in diagnostics, therapeutics, and elsewhere.
Nobel Laureate Dr. Jim Rothman, Dr. Melanie Mathieu of Prellis Biologics, and Daniel Dornbusch of Excision join host Michael Marks for an in-depth discussion covering advancements in CRISPR technology, the role of AI in drug discovery, the future of personalized medicine, and much more.
Legendary technology founder and venture investor Vinod Khosla joins host Michael Marks for a wide-ranging discussion on the future of AI, major tech cycles, the importance of being honest with founders, and much more. Vinod shares his predictions for the next 25 years of technology advancement and how we should be assessing the risks and benefits as the adoption of artificial intelligence continues to accelerate.
Celesta Capital is a global deep tech venture firm enabling visionary founders at the forefront of scientific and engineering breakthroughs.
Celesta's team has spent decades founding, leading, and scaling global technology businesses, collectively founding more than 40 companies. We understand how to partner with founders to help turn prototypes into powerhouses.
From semiconductors and systems to breakthrough biology, we seek out the physics‑defying, code‑rewriting breakthroughs that will power the next decade of technology advancement.
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