TechSurge: Deep Tech Podcast
Exploring topics at the intersection of emerging technology, geopolitics, and business.
Hosted by Celesta Capital.
The TechSurge: Deep Tech VC Podcast shares the latest insights directly from legendary Silicon Valley leaders, daring new founders, and visionary technologists.
Join us as we examine the factors shaping the next major technology cycle shift of AI, examine emerging global tech hubs, and analyze where investment dollars are flowing next.
Each discussion delves into the intersection of technology advancement, market dynamics, and the founder journey, offering insights into the vast opportunities and complex challenges ahead.
For entrepreneurs, investors, or anyone interested in where we're headed next, this is your guide to understanding the technologies and companies poised to transform the future.
The Race to Build the Next Trillion-Dollar AI Chip Company
Almost 2% of U.S. GDP will be spent on AI infrastructure this year, nearly double 2025's figure. But beneath those headline numbers, the composition of that spending has quietly flipped: for the first time, dollars spent on running models in production now outweigh dollars spent training them.
In this episode of TechSurge, host David Goldman speaks with Austin Lyons, a semiconductor analyst at Creative Strategies, co-host of the Semi Doped podcast, and author of the Chipstrat newsletter. Lyons previously worked as a hardware engineer at Intel and as a product manager on John Deere's autonomous tractor and Blue River Technology teams before turning to full-time chip industry analysis.
The conversation opens with why AI buyers have moved from assembling commoditized parts to buying entire pre-integrated systems, tracing how Nvidia's rack-scale approach, exemplified by its 72-GPU Grace Blackwell racks, made turnkey deployment the default, and why that raises the bar for any chip startup trying to compete. Lyons and Goldman then unpack how inference workloads have split into two distinct problems, prefill and decode, and how that split created an opening for SRAM-based challengers to outperform general-purpose GPUs on decode speed.
From there, the discussion turns to the rise of neoclouds, the GPU-rental companies that grew into public businesses worth well over $100 billion combined, and why so many traditional investors missed them. Lyons and Goldman work through the circular financing debate head-on: the mechanics of Nvidia's equity stakes, GPU-backed debt, and hyperscaler off-take agreements that critics compare to dot-com-era vendor financing, and the counterargument that demand is simply outrunning fixed supply.
The episode closes on Lyons's own framework for identifying the next trillion-dollar chip company, built on four conditions including the ability to run trillion-parameter models at rack scale, beat an incumbent on a key performance metric, and land a frontier anchor customer, along with a look at how AI-assisted chip design is lowering the barrier for more companies, from OpenAI to electric vehicle makers, to design their own custom silicon.
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Former CEO of PepsiCo and New York Times bestselling author Indra Nooyi joins host Michael Marks for a wide-ranging conversation to share her insights on the growth of big tech companies, the impact of AI, CEO-board relationships, and much more.
Indra currently serves on the boards of Amazon, Phillips, Memorial Sloan Kettering Cancer Center, the National Gallery of Art, and is a Dean’s Advisory Council Member at MIT School of Engineering. Her New York Times bestselling memoir My Life In Full offers insight and a call-to-action from one of the world’s most-admired business leaders on how our society can blend work and family — and advance women — in the 21st century. She is widely considered to be one of the world’s top CEOs for her leadership at global giant PepsiCo over 12 years.

Driven both by surging demand and rapid technology advancements, an emerging area of health innovation called “bioconvergence” is driving improvements in human health and sustained interest from investors. This episode will explore these new applications merging engineered technologies with scientific disciplines, including in diagnostics, therapeutics, and elsewhere.
Nobel Laureate Dr. Jim Rothman, Dr. Melanie Mathieu of Prellis Biologics, and Daniel Dornbusch of Excision join host Michael Marks for an in-depth discussion covering advancements in CRISPR technology, the role of AI in drug discovery, the future of personalized medicine, and much more.

Legendary technology founder and venture investor Vinod Khosla joins host Michael Marks for a wide-ranging discussion on the future of AI, major tech cycles, the importance of being honest with founders, and much more. Vinod shares his predictions for the next 25 years of technology advancement and how we should be assessing the risks and benefits as the adoption of artificial intelligence continues to accelerate.
Celesta Capital is a global deep tech venture firm enabling visionary founders at the forefront of scientific and engineering breakthroughs.
Celesta's team has spent decades founding, leading, and scaling global technology businesses, collectively founding more than 40 companies. We understand how to partner with founders to help turn prototypes into powerhouses.
From semiconductors and systems to breakthrough biology, we seek out the physics‑defying, code‑rewriting breakthroughs that will power the next decade of technology advancement.

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